Archer VARIANTPlex™ Solid Tumor Focus v2 panel

Identify DNA profiles of multiple cancers with one focused panel

Detect single nucleotide variants, copy number variations, insertions, deletions, and microsatellite instability status with NGS for 20 genes relevant for colorectal cancer, breast cancer, melanoma, NSCLC, and other solid tumor cancer research.

Detect confidently with Archer VARIANTPlex NGS panels for RNA.

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Learn how the VARIANTPlex Solid Tumor Focus v2 panel can identify key genomic alterations for your research.

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Product details

Panel specifications

Specifications
Targeted genes20
Genomic alterationsSNVs, indels, CNVs, ITDs, MSI
Input nucleic acid required*≥10 ng
Recommended number of reads1.5 M
Hands-on time<3.5 hours
Total library prep time1.5 days
Platform compatibilityIllumina®
Reagent formatLyophilized or liquid
Supported sample typesBlood, bone marrow, fresh frozen, FFPE, BMMC, PBMC

*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.

Gene targets

AKT1
BRAF
EGFR
ERBB2
FOXL2
GNA11
GNAQ
GNAS
HRAS
IDH1
IDH2
KIT
KRAS
MET
NRAS
PDGFRA
PIK3CA
RET
TERT
TP53

Interested in adding a few genes to this panel?

Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.

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Benefits

  • Detect confidently—A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Analysis empowers you to detect confidently.
  • Less QNSAnchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and potentially degraded samples such as FFPE tissue.
  • Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
  • Customize content—Use Assay Marketplace to modify any panel to fit your lab's needs or start from scratch to keep up with the pace of discovery.

Ready to start?

Talk with our technical sales team. Learn how the VARIANTPlex Solid Tumor Focus v2 panel can identify key genomic alterations for your research.

Request a consultation

Resources

Frequently asked questions

Related products

References

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